Pushing The Limits

This week on Pushing the Limits, we dive into the science of living longer and healthier with Chris Burres, a trailblasing carbon nano scientist and the mastermind behind ESS60—a game-changing molecule shaking up the world of longevity. Known as a refined, human-friendly version of Carbon 60, ESS60 is stealing the spotlight for its potential to boost lifespan, fight ageing, and supercharge wellness. Chris walks us through his incredible journey in nanotechnology, from the Nobel Prize-winning origins of Carbon 60 to the cutting-edge research that’s turning ESS60 into a longevity powerhouse. We’re talking antioxidant superpowers, inflammation-busting effects, and even mitochondrial tune-ups—science that could redefine how we age. Whether you’re obsessed with biohacking, intrigued by breakthroughs, or just want to feel your best, this episode is your ticket to the future of health. What You’ll Discover: The ESS60 Story: How a Nobel Prize-winning discovery evolved into a molecule you can use today. Science That

In this episode, host Lisa Tamati sits down with Dr. Eric Osansky, a leading expert in natural endocrine solutions, to explore the world of thyroid health. Focusing on hypothyroidism, Hashimoto’s thyroiditis, and Graves’ disease, Dr. Osansky unpacks how the gut, immune system, inflammation, nutrition, and genetics play pivotal roles in these conditions—and what you can do about it. Dr. Osansky, founder of Natural Endocrine Solutions, shares his personal journey of overcoming Graves’ disease using natural methods, inspiring his mission to help others reclaim their health. He’s the host of the popular podcast Save My Thyroid and the author of bestselling books like Natural Treatment Solutions for Hyperthyroidism and Graves’ Disease and Hashimoto’s Triggers. Plus, he offers a fantastic free 6-step guide on his website to kickstart your thyroid-healing journey. In this episode, we cover: The differences between hypothyroidism, Hashimoto’s, and Graves’—and their surprising connections.  How gut health (think l

Welcome back to the second part of the Aevum Labs Series on Immune Health! In this episode, we sit down with Dr. Elizabeth Yurth, founder of the Boulder Longevity Institute, to explore the fascinating world of immunosenescence—the ageing of the immune system—and its connection to inflammaging, chronic inflammation that accelerates aging. Dr. Yurth explains how the decline of our immune system not only affects our resilience to infections but also plays a pivotal role in the development of chronic diseases, neurodegeneration, and overall cellular decline. We dive into how gut health, immune health, and cellular health are deeply interconnected, with 70–80% of our immune system residing in and around the gut. Learn how chronic systemic inflammation and gut permeability can break down your immune defenses and how you can turn back the clock on immune ageing. We also introduce our exciting new product developed in conjunction with Dr Yurth as a scientific advisor, from Aevum Labs—Rejuvenate—which is specifically

In this final episode of our three-part series, we welcome back Dr. Bill Andrews, world-renowned telomere scientist and founder of Sierra Sciences. If you’ve been captivated by the journey through telomere science so far, you won’t want to miss this deep dive into the future of telomerase research and its groundbreaking potential to reverse ageing at the genetic level. In this episode, Dr. Andrews reflects on the progress made in telomere science and shares his latest insights on how telomerase activation could become a mainstream therapy for longevity and disease prevention. He also unpacks the challenges, opportunities, and what lies ahead in the quest for cellular rejuvenation. Key Discussion Points:  Telomerase Activation – Practical Applications & Next Steps What widespread telomerase activation could mean for ageing and chronic disease prevention. How telomerase therapies might revolutionise healthcare in the next decade.  New Discoveries in Telomere Research The most recent advancements and

In this deeply personal episode of "Pushing the Limits," Lisa Tamati shares her journey through the health sector, combining her expertise as a former professional ultra-endurance athlete with her role as a dedicated caregiver. Drawing on years of clinical research and personal experience caring for her mother through a series of health crises over the past decade, facing insurmountable odds over and over again—Lisa offers invaluable insights on brain rehabilitation, cancer therapies and insights, health optimisation and prevention strategies,  mental toughness, and the importance of self-care. Discussion Topics Include: Personal Journey & Background: How 25 years as an ultra-endurance athlete molded her resilience and approach to health. Transitioning from extreme sports to optimising health for herself, her mother, and her clients. Caring for Her Mother: Overcoming daunting challenges (aneurysm, stroke, cancer, gut issues,  infections, fractures) through relentless research and personalised

In this riveting second installment of our three-part series, Dr. Bill Andrews, one of the world’s foremost experts in telomere science, returns to dive deeper into the groundbreaking research on telomerase activation. If you were fascinated by Part 1, this episode takes the conversation to the next level—exploring cutting-edge advancements, the latest discoveries, and what it truly means to reverse cellular aging. Dr. Andrews, founder of Sierra Sciences, has dedicated his career to decoding the mechanisms behind telomere shortening and how activating telomerase could hold the key to longevity. This episode unpacks new breakthroughs in telomerase research and the practical applications that could change the way we approach aging and disease prevention. Key Discussion Points:

In this fascinating first instalment of a three-part series, we dive deep into the groundbreaking world of telomere science with Dr. Bill Andrews, a pioneering researcher in the field of ageing and longevity. Known for his revolutionary work on telomeres and their role in cellular aging, Dr. Andrews shares insights into how his research is paving the way for the ultimate goal: curing aging. Dr. Andrews, the founder of Sierra Sciences, has dedicated his life to understanding the root causes of ageing at the molecular level. This episode covers the basics of telomeres, the science behind their shortening, and why maintaining telomere length is essential for longevity and disease prevention. Key Discussion Points: What Are Telomeres? Telomeres are protective caps at the ends of chromosomes that safeguard our genetic material during cell division. As we age, telomeres shorten, leading to cellular dysfunction and ageing. Why Telomeres Matter in Aging: Telomere shortening is a major driver of ageing and

This week I have my very good friend and world renown cellular health expert, longevity specialist and orthopedic surgeon Dr Elizabeth Yurth  (MD, ABPMR, ABAARM, FAARM, FAARFM, FSSRP) of the Boulder Longevity Institute to guest.   Locked away in a vault somewhere deep inside the Boulder Longevity Institute lies the secret everyone wishes they could get their hands on – the supplement routine of Dr. Elizabeth Yurth. As Co-Founder and Chief Medical Officer of BLI, clients and non-clients alike long to know what perfect blend of supplementation Dr. Yurth uses. Someone in this position must have it down pat! Well, the disappointing answer is: One size does not fit all. What suits the current lifestyle, biology, and needs of Dr. Yurth may be a far cry from the needs of other individuals. We are all unique, and alas, so are our supplement requirements. However Dr. Yurth does offer an overview of supplements that are beneficial to virtually everyone. The areas of cell membrane, gut, and mitochondrial health are k

Welcome to a Groundbreaking Series on Immune Health with Aevum Labs! After over two years of development and backed by 15 years of clinical research, we're thrilled to introduce our flagship product - Re:Juvenate.—a revolutionary product targeting immune, gut, and cellular health. In this first episode, we speak with Dr. Rod Claycomb, co-founder of Quantec Ltd, to explore the science behind one of Re:Juvenate's key ingredients, IDP (Immune Defense Protein). About Aevum Labs Founded on a decade of research into aging, Aevum Labs targets immunosenescence, one of the core hallmarks of aging. We aim to offer a safe, effective solution for all, from the elderly to the young, focusing on immune, gut, and cellular health. The Science of Aging and Immunosenescence As we age, our immune system undergoes a decline in function known as immunosenescence. This process includes: Thymic Involution: Reduced T cell production. Reduced Immune Cells: Impaired proliferation of immune cells. Cytokine Dysregulation: Increase

In this eye-opening episode, we dive deep into the world of post-concussion syndrome (PCS) and brain health with Dr. Mark Allen of Cognitive FX, a leading expert in brain repair. PCS affects millions worldwide, yet many are left frustrated with lingering symptoms like brain fog, fatigue, and headaches. Dr. Allen shares his groundbreaking approach that combines the latest in neuroscience with a holistic, multidisciplinary method to treat and heal the brain. Key topics include: Why Functional MRI (fMRI) is a Game Changer: How it identifies hidden brain dysfunction and tailors treatments to individual needs. Integrated Healing Strategies: From vestibular rehabilitation and neuromuscular therapy to high-intensity interval training (HIIT) programs designed for the brain. Cognitive and Sensory Therapy: Rewiring the brain through targeted cognitive tasks and sensory integration work. The Role of Neurointegration and Occupational Therapy: Enhancing brain-body connections for long-term recovery. Timely Treat

In this fascinating episode, we sit down with the Founder of Kenetik Ketones, Devon Price to explore the cutting-edge world of exogenous ketones. Whether you're looking to optimise brain health, help after traumatic brain injury, concussions, alzheimers, dementia or just to enhance athletic performance, or unlock a cleaner energy source for your body, exogenous ketones could be the game-changer you've been waiting for. We dive into: What are exogenous ketones? Understanding how they mimic the natural state of ketosis and provide an immediate energy source for your brain and body. Brain health and repair: Discover how ketones support cognitive function, protect neurons, and aid in recovery from brain injuries. Clean energy source: Why ketones provide a more sustainable and efficient fuel than glucose. Weight loss and metabolic health: Learn how ketones help reduce hunger, support fat burning, and improve insulin sensitivity. Athletic performance: Enhance endurance, recovery, and overall physical outp

In this episode, we sit down with the brilliant Dr. Sam Shay, a functional and lifestyle medicine expert with over 20 years of experience. Dr. Shay shares his deep knowledge of functional medicine testing and genetic testing, explaining why preventative medicine is the key to optimizing health and avoiding chronic disease. We delve into how genetic testing can transform your approach to health by tailoring your diet, exercise, sleep, work habits, and overall lifestyle to your unique genetic blueprint. Dr. Shay emphasizes the need to move away from the outdated "reactive" model of healthcare and embrace proactive strategies to unlock your health potential. Whether you're looking to improve your energy, manage stress, or optimize your performance, this episode offers actionable insights to help you live your best life.  What You'll Learn: Why functional medicine testing provides a comprehensive view of your health. The power of genetic testing to personalize your diet, fitness, and lifestyle. How to use y

In this episode, we dive deep into the science of muscle health with Dr. Chris Meletis, exploring why maintaining muscle mass is critical as we age and how MYOS MD's revolutionary supplement, Fortetropin, can play a pivotal role in combating muscle loss. Key Topics Covered: The Importance of Muscle for Longevity: Muscles act as the currency of longevity, influencing metabolism, physical functionality, myokine production, hormone balance, and overall musculoskeletal health. After age 40, muscle loss (sarcopenia) accelerates, with lean body mass decreasing by 1-2% annually and strength declining 1.5-5% per year. This impacts mobility, independence, and systemic health. Understanding Myostatin and Its Role: Myostatin is a natural protein that inhibits muscle growth, preventing excess muscle accumulation. While beneficial in early development, elevated myostatin levels with age, injury, or illness can exacerbate muscle wasting and hinder recovery. How MYOS MD's Fortetropin Helps: Fortetropin, derived f

In this fascinating episode, we're joined by Dr. Dayan Goodenowe, a visionary neuroscientist and founder of Prodrome Sciences, to explore the groundbreaking potential of plasmalogens in restoring health and optimizing longevity. Dr. Goodenowe's work is transforming how we approach chronic conditions, such as Alzheimer's, Parkinson's, autism, multiple sclerosis (MS), long COVID, and cardiovascular issues. We discuss the role of plasmalogens, Prodrome Sciences' advanced diagnostic tools, and how his Restorative Health Centre is making these innovations accessible for proactive health management. Episode Highlights 1. What Are Plasmalogens, and Why Are They Essential? Dr. Goodenowe explains the critical role of plasmalogens, unique lipids that maintain cell membrane integrity, support the immune system, and regulate oxidative stress. These lipids, particularly abundant in the brain and heart, are essential for neuron function, immune resilience, and cardiovascular health. Research shows that low levels of plasma

In this weeks episode, we will have the part two of Carol Peterson' episode.  Carol Peterson from The Wellness by Design Project , an expert in bioidentical hormone replacement therapy (BHRT) and women's health. Carol shares her in-depth knowledge and experience with the powerful benefits of progesterone and BHRT for a wide range of health issues. From treating conditions like endometriosis, fibroids, perimenopause, and menopausal symptoms to addressing miscarriages, heavy bleeding, and hormonal imbalances, Carol explains how progesterone plays a key role in improving both physical and mental health. Join us as we dive into the science behind Progesterone and BHRT, explore how it supports brain health, assists in managing thyroid health, and even has promising uses for brain injuries and trauma recovery. Whether you're looking to learn more about hormone health or seeking holistic options for managing reproductive and neurological health challenges, this conversation is packed with valuable insights. Key Di

In this episode, we're thrilled to welcome Carol Peterson from The Wellness by Design Project, an expert in bioidentical hormone replacement therapy (BHRT) and women's health. Carol shares her in-depth knowledge and experience with the powerful benefits of progesterone and BHRT for a wide range of health issues. From treating conditions like endometriosis, fibroids, perimenopause, and menopausal symptoms to addressing miscarriages, heavy bleeding, and hormonal imbalances, Carol explains how progesterone plays a key role in improving both physical and mental health. Join us as we dive into the science behind Progesterone and BHRT, explore how it supports brain health, assists in managing thyroid health, and even has promising uses for brain injuries and trauma recovery. Whether you're looking to learn more about hormone health or seeking holistic options for managing reproductive and neurological health challenges, this conversation is packed with valuable insights. Key Discussion Points: 1. Introduction to Bi

In this episode, we are joined by Dr. Melvin Nario, MD, HMD, an integrative and homeopathic medical doctor with a diverse background that spans conventional and alternative medicine. With his training in both traditional Western medicine and homeopathy, Dr. Nario takes a holistic approach to healthcare, focusing on personalized treatments that address the root causes of illness. He is particularly known for his expertise in peptide therapies, anti-aging medicine, and integrative oncology, combining cutting-edge science with natural healing methods.  Episode Highlights: Dr. Nario's Medical Journey**: Learn about Dr. Nario's unique path, from his medical degree at the University of Santo Tomas in the Philippines to becoming a licensed homeopathic doctor in Nevada, integrating both worlds of medicine. Peptide Therapy**: Discover the exciting potential of peptide therapies in enhancing healing, boosting immune function, and supporting anti-aging. Dr. Nario shares how these therapies can regulate hormones, impro

In this conversation, Lisa Tamati interviews Kyal Van Der Leest, a naturopath and formulator from Lvlup Health. Kyal shares his personal journey, which began with his mother's cancer diagnosis, leading him to study nutrition and explore alternative therapies. The discussion covers the impact of hyperbaric oxygen therapy, the role of peptides in health, and the importance of quality sourcing in supplements. Kyal also delves into the significance of zonulin in gut health and the effects of chronic inflammation on aging. In this conversation, Lisa Tamati and Kyal from LVLUP Health delve into the complexities of chronic inflammation, neuroprotective peptides, and the importance of effective detoxification strategies. They discuss the role of liposomal delivery in enhancing peptide absorption, the significance of creatine and guanidinoacetic acid for brain health, and the intricate nature of methylation. They also talk about liver health, detoxification pathways, binders, mold toxicity, the important of having str

In this episode, Lisa Tamati discusses the complexities of brain injuries with her manager, Georgia Ferris. They explore various types of brain injuries, including traumatic and non-traumatic causes, and the importance of recognizing past injuries that may affect current health. The conversation delves into diagnostic methods, the role of nutrition, particularly the benefits of a ketogenic diet, and the significance of peptides and hyperbaric oxygen therapy in rehabilitation. Lisa emphasizes the need for lifestyle changes, including exercise and sleep hygiene, to support brain health and recovery Takeaways Brain injuries can be traumatic or non-traumatic, affecting many aspects of health. Many people may not recognize past brain injuries that impact their current health. Diagnostic methods for brain injuries include scans and hormone testing. Nutrition plays a crucial role in brain rehabilitation, with a focus on whole foods. The ketogenic diet can provide an alternative energy source for the brain. Peptides

In this weeks episode of "Pushing the Limits" , Dr. David Furman, Director of the 1000 immunomes project, the world's largest longitudinal population-based study of immunology and aging at Stanford University and Associate Professor at the Buck Institute for Aging, Founder of Edifice Health and Cosmica Biosciences, discusses his extensive research in immunology, particularly focusing on the 1000 Immunomes Project, which aims to understand the immune system's role in aging.  He emphasizes the importance of studying human biology over traditional animal models and introduces the concept of the Inflammation Age Clock as a new biomarker for aging.  The discussion also covers the implications of systemic chronic inflammation in aging, the role of nutrition, and the potential for interventions to improve health span. Additionally, Dr. Furman shares insights into his work with NASA on accelerated aging in astronauts, highlighting the broader applications of his research in combating age-related diseases.   Takeaway